The 2021 ESS Safety & Reliability Forum provides a platform for discussing the current state of ESS Safety & Reliability and stratagems for improving cell-to-system level safety and reliability. This forum will provide an overview of work in, and creating the future of, energy storage safety and reliability. It offers a unique mix of learning from subject matter experts and stakeholders in energy storage. While speakers to this forum have mostly been selected, a small number of speaking slots may still be available by contacting the Joshua Lamb at jlamb@sandia.gov.